PERIODS

WITHOUT PAIN

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NO HORMONES.
NO SYSTEMIC SIDE-EFFECTS.
LOCAL APPLICATION.
A SOLUTION DESIGNED
SPECIFICALLY FOR PERIOD PAIN.

Menstrual health needs radical transformation. A long-term solution for menstruating people is long overdue. 1.8 billion people in the world menstruate. 1.4 billion suffer from menstrual pain every month. 42 million people have pain so severe they're forced to skip work, school, social activities and sports.  

Existing solutions either entail hormone-based treatments or pain medication in high dosages. Both solutions are often linked to severe systemic side-effects. It’s simply not good enough.  

Woman experiencing period pain

MelioOne

PERIOD PAIN MANAGEMENT WITHOUT CYCLE DISRUPTION.

MelioOne helps take that pain away with no systemic side-effects and without interfering with your natural menstrual cycle.

What is it? It’s an IUD with a continuous and slow-release mechanism to administer pain medication over the course of one year. The dosage is equivalent to 1 painkiller tablet such as Ibuprofen 400.

Period Pain IUD

LATEST NEWS.

20.03.2025

Meliodays Medical announces the closing of a pre-seed financing round of over €800,000

Addressing a high unmet medical need in menstrual pain with microdoses of painkillers through local application.

OUR DEVELOPMENTAL JOURNEY.

MelioOne is in prototyping phase to test out the polymer-technology that enables the low and slow-release mechanism. We are currently on track with timeline projections and working towards the start of Pre-Clinical Trials by the fourth quarter this year. It will not be until 2029 that we can enter the market with a solution that has been proven safe and effective in clinical trials.

WE’RE A WOMAN-LED PHARMACEUTICAL COMPANY THAT BELIEVES IN EMPOWERMENT THROUGH INNOVATION.

Image of CEO Simone

OUR STORY STARTED WITH A QUESTION

WHY AREN’T THERE MORE EFFECTIVE AND SUSTAINABLE SOLUTIONS FOR PERIOD PAIN?

My female colleagues, friends and family would often share that their period pains left them feeling disempowered not just at work but in life. Many felt guilty for not being able to perform or be 100% present as a boss, colleague, a mother or a friend. The more these conversations happened, the more I realized how under-recognized and stigmatized period pain still is. 

When I spoke to my brother, Benjamin about it, he shared his experience as a gynecologist and stated, “if it was a problem also affecting men, it would be solved by now”. That was my lightbulb moment to start Meliodays.

Meliodays was founded in equal parts to solve a medical condition while serving and pursuing health equality. Together with Benjamin and my husband Martin, we realized we had complementary skills and backgrounds to make it a reality. 

Today, period pain continues to be a silent condition and a taboo topic instead of a health priority. That’s why we’re working hard to create a period pain solution that targets the problem at its source, is hormone-free and safe to use long term. Our goal is for menstruating people to be able to say, “no more pain, period”. 

With Love, 
Simone